Cellular and Molecular Biology of the Kidney. Are all accomplished by intricate mechanisms of renal response. This breadth of physiology hinges on the clever ingenuity of nephron architecture that evolved as complex organisms came out of water to live on land. Kidneys develop from intermediate mesoderm under the timed or sequential control of a growing number of genes. Determinants and Regulation of Glomerular Filtration. Within the capillary lumen, d.

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